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The main function of the endocannabinoid system is to regulate and maintain bodily homeostasis, while keeping the biological harmony of our body in place in response to environmental changes. The cannabinoids that come from cannabis also interact with many other receptors in the brain, a good example being CBD. Because of binding to more receptors, cannabinoids induce different effects than endocannabinoids, even if they activate the same cannabinoid receptors. Research has shown that small doses of cannabinoids from cannabis can signal the body to make more endocannabinoids and build more cannabinoid receptors. This is why many first-time cannabis users don’t feel an effect, but by their second or third time using the herb they have built more cannabinoid receptors and are ready to respond.
We now know that the endocannabinoid system helps a myriad of bodily systems maintain balance —everything from keeping a healthy bone density all the way to naturally preventing diabetes. Because of the studies showing how cannabinoids can help mental illnesses like depression and anxiety, neuroscientists are now looking at the role of the whole endocannabinoid system in controlling anxiety.
More receptors increase a person’s sensitivity to cannabinoids; smaller doses have larger effects, and the individual has an enhanced baseline of endocannabinoid activity. I believe that small, regular doses of cannabis might act as a tonic to our most central physiologic healing system. By working backwards, researchers traced the effects of cannabinoids back to the endocannabinoid system, or the system of cannabinoid receptors and chemicals made by our brains.
The endocannabinoid system is a biological signaling system in the body that uses endocannabinoids, receptors, and enzymes to create a state of homeostasis. Homeostasis is when the body is in a balanced state and the functions in the body are regulated properly.
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- While their selection is small CBD-a, their oils are relatively inexpensive.
- These oils are on the higher end of the potency spectrum, making them more suited to more severe conditions.
- It should be noted that only a portion of their hemp farms is organic; however, they’re looking to be fully organic by 2022.
- Some people may be put off by the lack of flavors and straightforward packaging.
- Flavors include Wintermint, Blood Orange, Tropical Breeze, and Flavorless.
- Independent lab testing ensures that the amount of CBD and THC is the same as on the label.
Cannabinoids generally come from two places — the human body or the cannabis plant. However, there is a third place that is important to consider, a lab. Cannabinoids can be produced synthetically and distributed on the market. Marinol and Cesamet are synthetic versions of THC that have FDA approval to be marketed and sold as a prescription drug. Synthetic cannabinoids do bind the endocannabinoid system to produce effects, but they often fail to incorporate one of the most important ideas in the medical cannabis community, the entourage effect.
When the body doesn’t produce enough endocannabinoids, there cannot be an equilibrium in the body, and health issues can occur. Some factors that may affect the production of endocannabinoids in the body are a person’s diet, exercise, and sleep. The ECS may be stimulated by CBD oil due to its ability to interact with cannabinoid receptors and block enzymes to improve the effectiveness of endocannabinoids. The endocannabinoid system is an essential and impactful part of the human body. The first is that every human being on the planet has an inbuilt endocannabinoid system.
The second is that our endocannabinoid system is made up of receptors. Our bodies are designed with a biological system made up of endocannabinoids called the endocannabinoid system. Endocannabinoids are internal lipid-based neurotransmitters that have the ability to combine themselves with cannabinoid receptors located throughout our body. The endocannabinoid system releases our own cannabinoid molecules that are organically made in our body, and these cannabinoids interact with different receptors to produce different results.